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Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal [MA352B-100 or MA352B-025]

$350.00
SKU:
MA352B-100
Quantity:
Description
Specifications
Ordering
Documents

Product Description

Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal [MA352B-100 or MA352B-025] 

The tumor necrosis factor (TNF) superfamily (TNFSF) of cytokines and TNF receptor superfamily (TNFRSF) display diverse physiological functions and play critical roles in the development and homeostasis of the immune-, nervous-, and musculoskeletal-systems in mammals. Abnormal expression of TNF family cytokines or their receptors has been linked to a host of major human diseases including arthritis, psoriasis, osteoporosis, and cancer (Reference 1, see below). Elevated localized expression of TNFα (TNF alpha) has been shown to be one of the underlying causes for various autoimmune and inflammatory disorders such as psoriasis and arthritis. Biologic therapies blocking TNFα such as TNFRII-Fc (Etanercept with the brand name Enbrel marketed by Amgen) currently represent one of the largest-selling class of blockbuster drugs globally.

GenHunter has 3 TNFRII monoclonal antibodies (a neutralizing mAb and 2 binding mAbs) recognizing Etanercept as well as a recombinant human TNFR2-Fc fusion protein.


TNF/TNFRII Superfamily Antibody & Antigen Products Available:

Product Description   Clone   Isotype  Specificity          Volume   Applications

  Cat. No.                         

Click to Order

Tumor Necrosis Factor (TNF) superfamily 4-1BBL
Neutralizing Antibody, Mouse Monoclonal
9G3    Not tested

4-1BBL

100µg
or 25µg

NAb,ELISA,WB

MA351N-100

MA351N-025

Order
Tumor Necrosis Factor (TNF) superfamily 4-1BBL
Binding Antibody, Mouse Monoclonal
31H9-B4    Not tested

4-1BBL

100µg
or 25µg 

ELISA,WB

MA351B-100

MA351B-025

Order
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal 4B3-D4    Not tested

OX40L

100µg
or 25µg 

ELISA,WB

MA352B-100

MA352B-025

Order
Recombinant Human TNFR2-Fc Fusion Protein      

 

100µg
or 25µg 

 

MP202-100

MP202-025

Order

We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus)HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).


References:

  1. Yang, X. et al: Functional detection of TNF receptor family members by affinity-labeled ligands. (2017) Scientific Reports. 7:694. https://www.nature.com/articles/s41598-017-06343-4

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Antibody Specifications
Antibody Name

Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal

Clone No. 4B3-D4
Class Mouse Monoclonal
Catalog No / SKU MA352B-100 (for 100 µg) or MA352B-025 (for 25 µg)
IgG subtype Not tested
Specificity OX40L
Binding / Neutralizing mAb        Binding mAb
Volume 25 or 100 ug
Provided as Liquid
Applications ELISA: antigen binding affinity EC50 = 30 ng/mL
Western Blot at 1:800 - 1:2000
Concentration ~ 1 mg/mL
Purification G protein affinity purified, >99% determined by HPLC
Storage conditions Store at -20°C long term, Avoid freeze / thaw cycle

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Documents

 

TNF/TNFRII Superfamily Antibody & Antigen Products Available:

Product Description   Clone   Isotype  Specificity          Volume   Applications

  Cat. No.                         

Click to Order

Tumor Necrosis Factor (TNF) superfamily 4-1BBL
Neutralizing Antibody, Mouse Monoclonal
9G3    Not tested

4-1BBL

100µg
or 25µg

NAb,ELISA,WB

MA351N-100

MA351N-025

Order
Tumor Necrosis Factor (TNF) superfamily 4-1BBL
Binding Antibody, Mouse Monoclonal
31H9-B4    Not tested

4-1BBL

100µg
or 25µg 

ELISA,WB

MA351B-100

MA351B-025

Order
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal 4B3-D4    Not tested

OX40L

100µg
or 25µg 

ELISA,WB

MA352B-100

MA352B-025

Order
Recombinant Human TNFR2-Fc Fusion Protein      

 

100µg
or 25µg 

 

MP202-100

MP202-025

Order

We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus)HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).



All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.