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- Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal [MA352B-100 or MA352B-025]
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal [MA352B-100 or MA352B-025]
Product Description
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal [MA352B-100 or MA352B-025]
The tumor necrosis factor (TNF) superfamily (TNFSF) of cytokines and TNF receptor superfamily (TNFRSF) display diverse physiological functions and play critical roles in the development and homeostasis of the immune-, nervous-, and musculoskeletal-systems in mammals. Abnormal expression of TNF family cytokines or their receptors has been linked to a host of major human diseases including arthritis, psoriasis, osteoporosis, and cancer (Reference 1, see below). Elevated localized expression of TNFα (TNF alpha) has been shown to be one of the underlying causes for various autoimmune and inflammatory disorders such as psoriasis and arthritis. Biologic therapies blocking TNFα such as TNFRII-Fc (Etanercept with the brand name Enbrel marketed by Amgen) currently represent one of the largest-selling class of blockbuster drugs globally.
GenHunter has 3 TNFRII monoclonal antibodies (a neutralizing mAb and 2 binding mAbs) recognizing Etanercept as well as a recombinant human TNFR2-Fc fusion protein.
TNF/TNFRII Superfamily Antibody & Antigen Products Available:
Product Description | Clone | Isotype | Specificity | Volume | Applications |
Cat. No. |
Click to Order |
Tumor Necrosis Factor (TNF) superfamily 4-1BBL Neutralizing Antibody, Mouse Monoclonal |
9G3 | Not tested |
4-1BBL |
100µg or 25µg |
NAb,ELISA,WB |
Order | |
Tumor Necrosis Factor (TNF) superfamily 4-1BBL Binding Antibody, Mouse Monoclonal |
31H9-B4 | Not tested |
4-1BBL |
100µg or 25µg |
ELISA,WB |
Order | |
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal | 4B3-D4 | Not tested |
OX40L |
100µg or 25µg |
ELISA,WB |
Order | |
Recombinant Human TNFR2-Fc Fusion Protein |
|
100µg or 25µg |
|
Order |
We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus), HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).
References:
- Yang, X. et al: Functional detection of TNF receptor family members by affinity-labeled ligands. (2017) Scientific Reports. 7:694. https://www.nature.com/articles/s41598-017-06343-4
All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Antibody Specifications | |
Antibody Name |
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal |
Clone No. | 4B3-D4 |
Class | Mouse Monoclonal |
Catalog No / SKU | MA352B-100 (for 100 µg) or MA352B-025 (for 25 µg) |
IgG subtype | Not tested |
Specificity | OX40L |
Binding / Neutralizing mAb | Binding mAb |
Volume | 25 or 100 ug |
Provided as | Liquid |
Applications | ELISA: antigen binding affinity EC50 = 30 ng/mL Western Blot at 1:800 - 1:2000 |
Concentration | ~ 1 mg/mL |
Purification | G protein affinity purified, >99% determined by HPLC |
Storage conditions | Store at -20°C long term, Avoid freeze / thaw cycle |
All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Documents
TNF/TNFRII Superfamily Antibody & Antigen Products Available:
Product Description | Clone | Isotype | Specificity | Volume | Applications |
Cat. No. |
Click to Order |
Tumor Necrosis Factor (TNF) superfamily 4-1BBL Neutralizing Antibody, Mouse Monoclonal |
9G3 | Not tested |
4-1BBL |
100µg or 25µg |
NAb,ELISA,WB |
Order | |
Tumor Necrosis Factor (TNF) superfamily 4-1BBL Binding Antibody, Mouse Monoclonal |
31H9-B4 | Not tested |
4-1BBL |
100µg or 25µg |
ELISA,WB |
Order | |
Tumor Necrosis Factor (TNF) superfamily OX40L Binding Antibody, Mouse Monoclonal | 4B3-D4 | Not tested |
OX40L |
100µg or 25µg |
ELISA,WB |
Order | |
Recombinant Human TNFR2-Fc Fusion Protein |
|
100µg or 25µg |
|
Order |
We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus), HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).
All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.