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Nplate (Romiplostim) mAbs
Nplate (Romiplostim) is a thrombopoietin receptor (TPO-R) agonist marketed by Amgen for the treatment of thrombocytopenia. It has been approved for the treatment of both adult and pediatric patients with immune thrombocytopenia (ITP), a condition that occurs when the blood platelet count is too low. Nplate (Romiplostim) is a recombinant human IgG Fc fusion protein produced in E. coli.
GenHunter has 2 neutralizing monoclonal antibodies against Nplate (Romiplostim): Clone 5D5-G2 and Clone 2A3-B6. These NAbs have specificity against TPO-R Mimetic Peptide (Nplate).