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AP-TAG References

This is a list of references using GenHunter's AP-TAG technology.

For information about the AP-TAG technology, visit

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24. Koppel, A.M. et al: A 70 amino acid region within the semaphorin domain activates specific cellular response of semaphorin family members. Neuron. 1997, 19:531-537.

25. Feiner, L. et al: Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ. Neuron. 1997, 19:539-545.

26. Chen, H. et al: Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the Semaphorins Sema E and Sema IV but not Sema III. Neuron. 1997, 19:547-559.

27. Takahashi, T. et al: Neuronal and non-neuronal collapsin-1 binding sites in developing chick are distinct from other semaphorin binding sites. Journal of Neuroscience. 1997, 17:9183-9193.

28. Bonneh-Barkay, D. et al: Identification of glypican as a dual modulator of the biological activity of fibroblast growth factors. J. Biol. Chem. 1997, 272:12415-12421.

29. Monschau, B. et al: Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons. EMBO J. 1997, 16:1258-1267.

30. Labrador, J.P. et al: The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling. EMBO J. 1997, 16:3889-3897.

31. Adams, R.H. et al: The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing. EMBO J. 1997, 16:6077-6086.

32. Brennan, C. et al: Two Eph receptor tyrosine kinase ligands control axon growth and may be involved in the creation of the retinotectal map in the zebrafish. Development. 1997, 124:655–664.

33. Johnston, S. H. et al. A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development. 1997, 124:2245–2254.

34. Polleux, F. et al.: Patterning of cortical efferent projections by semaphorin-neuropilin interactions. Science. 1998, 282:1904-1906.

35. Takahashi, T. et al: Semaphorins A and E act a antagonists of neuropilin-1 and agonists of neuropilin-2 receptors. Nature Neuroscience. 1998, 1:487-493.

36. Nakamura, F. et al: Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse. Neuron. 1998, 21:1093-1100.

37. Giger, R.J. et al.: Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity. Neuron. 1998, 21:1079-1092.

38. Chen, H. et al: Semaphorin–neuropilin interactions underlying sympathetic axon responses to class III semaphorins. Neuron. 1998, 21:1283-1290.

39. Feldheim, D.A. et al: Topographic guidance labels in a sensory projection to the forebrain. Neuron. 1998, 21:1303-1313.

40. Denda, S. et al: Identification of osteopontin as a novel ligand for the integrin alpha 8 beta 1 and potential roles for this integrin-ligand interaction in kidney morphogenesis. Mol. Biol. Cell. 1998, 9:1425-1435.

41. Ichijo, H. and Bonhoeffer F.: Differential withdrawal of retinal axons induced by a secreted factor. J. Neurosci. 1998, 18:5008-5018.

42. Durbin, L. et al.: Eph signaling is required for segmentation and differentiation of the somites. Gene Dev. 1998, 12:3096-3109.

43. Kang, J.S. et al.: CDO, a Robo-related cell surface protein that mediates myogenic differentiation. J. Cell Biology. 1998, 143:403-413.

44. Escribano, L. et al: Expression of the c-kit (CD117) molecule in normal and malignant hematopoiesis. Leukemia Lymphoma. 1998, 30:459-466.

45. Brose, K. et al: Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell. 1999, 96:795-806.

46. Li, H.S. et al.: Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons. Cell. 1999, 96:807-818.

47. Tamagnone, L. et al.: Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell. 1999, 99:71-80.

48. Senzaki, K. et al: Proteins of the CNR family are multiple receptors for reelin. Cell. 1999, 99:635-647.

49. Chin-Sang, I.D. et al.: The ephrin VAB-2/EFN-1 functions in neuronal signaling to regulate epidermal morphogenesis in C. elegans. Cell. 1999, 99:781-790.

50. Ba-Charvet, K.T.N. et al: Slit2-mediated chemorepulsion and collapse of developing forebrain axons. Neuron. 1999, 22:463-473.

51. Burstyn-Cohen, T. et al.: F-spondin is required for accurate pathfinding of commissural axons at the floor plate. Neuron. 1999, 23:233-246.

52. Jiang, P.H. et al: Integrin-associated protein is a ligand for the P84 neural adhesion molecule. J. Biol. Chem. 1999, 274:559-562.

53. Chellaiah, A. et al.: Mapping ligand binding domains in chimeric fibroblast growth factor receptor molecules - Multiple regions determine ligand binding specificity. J. Biol. Chem. 1999, 274:34785-34794.

54. Sher, I. et al.: Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs. J. Biol. Chem. 1999, 274:35016-35022.

55. Berman, B. et al.: Similarities and differences between the effects of heparin and glypican-1 on the bioactivity of acidic fibroblast growth factor and the keratinocyte growth factor. J. Biol. Chem. 1999, 274:36132-36138.

56. Behar, O. et al.: Semaphorin 3A growth cone collapse requires a sequence homologous to tarantula hanatoxin. Proc. Natl. Acad. Sci. USA. 1999, 96:13501-13505.

57. Ishiguro, Y. et al: The role of amino acids surrounding tyrosine 1062 in Ret in specific binding of the Shc phosphotyrosine-binding domain. Endocrinology. 1999, 140:3992-3998.

58. Walter, J.J. and Sane, D.C.: Angiostatin binds to smooth muscle cells in the coronary artery and inhibits smooth muscle cell proliferation and migration in vitro. Arterioscler, Thromb. & Vasc. Biol. 1999, 19:2041-2048.

59. Feinstein, Y. et al.: F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neurons. Development. 1999, 126:3637-3648.

60. Oohashi, T. et al.: Mouse ten-m/odz is a new family of dimeric type II transmembrane proteins expressed in many tissues. J. Cell Biology. 1999, 145:563-577.

61. Miyazaki, N. et al.: Mouse semaphorin H inhibits neurite outgrowth from sensory neurons. Neurosci. Res. 1999, 33:269-274.

62. Haj, F. et al: Retinotectal ligands for the receptor tyrosine phosphatase CRYP alpha. Mol. Cell Neurosci. 1999, 14:225-240.

63. Runko, E. et al: Cloning and expression of VEMA: A novel ventral midline antigen in the rat CNS. Mol. Cell Neurosci. 1999, 14:428-443.

64. Yue, Y. et al.: Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5. J. Neurosci. 1999, 19:10026-10035.

65. Seidel, S.D. and Denison M.S.: Differential gene expression in wild-type and Arnt-defective mouse hepatoma (Hepa1c1c7) cells. Toxicol. Sci. 1999, 52:217-225.

66. Polleux, F. et al: Semaphorin 3A is a chemoattractant for cortical apical dendrites. Nature. 2000, 404:567-573.

67. Oelgeschlager, M. et al.: The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling. Nature. 2000, 405:757-763.

68. Moloney, D.J. et al: Fringe is a glycosyltransferase that modifies Notch. Nature. 2000, 406:369-375.

69. Bruckner, K. et al: Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature. 2000, 406:411-415.

70. Hicks, C. et al: Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2. Nature Cell Biology. 2000, 2:515-520.

71. Hattori, M. et al: Regulated cleavage of a contact-mediated axon repellent. Science. 2000, 289:1360-1365.

72. Yan, M.H. et al.:Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science. 2000, 290:523-527.

73. Feldheim, D.A. et al: Genetic analysis of Ephrin-A2 and Ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping. Neuron. 2000, 25:563-574.

74. Nakagawa, S. et al: Ephrin-B regulates the ipsilateral routing of retinal axons at the optic chiasm. Neuron. 2000, 25:599-610.

75. Flanagan, J.G. et al.: Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos. Methods in Enzymology. 2000, 327:19-35.

76. Cullen, B.R.: Utility of the secreted placental alkaline phosphatase reporter enzyme. Methods in Enzymology. 2000, 326:159-164.

77. Flanagan, J.G. and Cheng, H.J.: Alkaline phosphatase fusion proteins for molecular characterization and cloning of receptors and their ligands. Methods in Enzymology. 2000, 327:198-210.

78. He, Y.N. et al.: Interaction of the poliovirus receptor with poliovirus. Proc. Natl. Acad. Sci. USA. 2000, 97:79-84.

79. Tjoelker, L.W. et al.: Structural and functional definition of the human chitinase chitin-binding domain. J. Biol. Chem. 2000, 275:514-520.

80. Lu, D. et al: Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies. J. Biol. Chem. 2000, 275:14321-14330.

81. Zhang, R. et al: Identification of a novel ligand-receptor pair constitutively activated by ras oncogenes. J. Biol. Chem. 2000, 275:24436-24443.

82. Kato, M. et al: Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases. Mol. Cell. Biol. 2000, 11:93-101.

83. Flanagan, J.G.: In situ analysis of embryos with receptor or ligand fusion protein probes. Current Biology. 2000, 10:R52-R53.

84. Rohm, B. et al.: Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A. Mech. Develop. 2000, 93:95-104.

85. Rulifson, E.J. et al: Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless. Mol. Cell. 2000, 6:117-126.

86. Mueller, B.K. et al: The receptor tyrosine phosphatase CRYP alpha affects growth cone morphology. J. Neurobiology. 2000, 44:204-218.

87. Taylor, V. et al: Membrane topology of peripheral myelin protein 22. J. Neurosci. Research. 2000, 62:15-27.

88. Long, Q.M. et al.: The zebrafish scyba gene encodes a novel CXC-type chemokine with distinctive expression patterns in the vestibulo-acoustic system during embryogenesis. Mech. Develop. 2000, 97:183-186.

89. Yan, M.H. et al.: Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity. 2000, Nat. Immunology. 1:37-41.

90. Cao, X. et al: Molecular cloning and characterization of a novel CXC chemokine macrophage inflammatory protein-2 chemoattractant for human neutrophils and dendritic cells. J. Immunology. 2000, 165:2588-2595.

91. Youn, B.S. et al: Chemokines, chemokine receptors and hematopoiesis. Immunology Review. 2000, 177:150-174.

92. Tokumaru, S. et al: Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J. Cell Biology. 2000, 151:209- 220.

93. Kawai, K. et al: Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation. Cancer Research. 2000, 60:5254-5260.

94. Kato, M. et al: Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases. Mol. Biol. of the Cell. 2000, 11:93-101.

95. Marsters, S.A. et al: Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Current Biology. 2000, 10:785-788.

96. Boissan, M. et al.: c-Kit and c-kit mutations in mastocytosis and other hematological diseases. J. Leukocyte Biol. 2000, 67:135-148.

97. Tsuboi, I. et al: Role of the membrane form of human colony-stimulating factor-1 (CSF-1) in proliferation of multipotent hematopoietic FDCP-mix cells expressing human CSF-1 receptor. Leukemia. 2000, 14:1460-1466.

98. Fournier, A.E. et al: Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature. 2001, 409:341-346.

99. Karumanchi, S.A. et al: Cell surface glypicans are low-affinity endostatin receptors. Molecular Cell. 2001, 7:811-822. 

100. Lee, Y.-N. et al: Identification of a role for the sialomucin CD164 in myogenic differentiation by signal sequence trapping in yeast. Mol. Cell. Biol. 2001, 21:7696-7706.

101. Olin, A.I. et al: The proteoglycans aggrecan and versican form networks with fibulin-2 through their lectin domain binding. J. Biol. Chem. 2001, 276:1253-1261.

102. Chen, R.L.and Lander, A.D.: Mechanisms underlying preferential assembly of heparan sulfate on Glypican-1. J. Biol. Chem. 2001, 276:7507-7517.

103. Qiao, S. et al: Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins. J. Biol. Chem. 2001, 276:9460-9467.

104. Semenov, M.V. et al: Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Current Biology. 2001, 11:951-961.

105. Ba-Charvet, K.T.N. et al: Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance. Journal of Neuroscience. 2001, 21:4281-4289.

106. Yiu, G.K. et al: SPARC (secreted protein acidic and rich in cysteine) induces apoptosis in ovarian cancer cells. American Journal of Pathology. 2001, 159:609-622.

107. Neumann, F.R. et al: An alternative amino terminus expressed in the central nervous system converts agrin to a type II transmembrane protein. Mol. Cell Neurosci. 2001, 17:208-225.

108. Asakura, M. et al: Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy. Nature Medicine. 2002, 8:35-40.

109. Mann, F. et al: Topographic mapping in dorsoventral axis of the Xenopus retinotectal system depends on signaling through Ephrin-B ligands. Neuron. 2002, 35:461-473.

110. Cyr, J.L. et al: Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains. Journal of Neuroscience. 2002, 22: 2487-2495.

111. Niederöst, B. et al: Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1. Journal of Neuroscience. 2002; 22:10368-10376.

112. Oh, H. et al: Selective induction of neuropilin-1 by vascular endothelial growth factor (VEGF): A mechanism contributing to VEGF-induced angiogenesis. Proc. Natl. Acad. Sci. USA. 2002, 99:383-388.

113. Aricescu, A.R. et al: Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma. Mol. Cell. Biol. 2002, 22:1881-1892.

114. Waterhouse, R. et al: Murine CD9 is the receptor for pregnancy-specific glycoprotein 17. J. Experimental Medicine. 2002, 195:277-282.

115. Li, Y. et al: Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis. J. Experimental Medicine. 2002, 195:1575-1584.

116. Kang, J.-S. et al: BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation. EMBO J. 2002, 21:114-124.

117. Wang, M. et al: Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.J. Biol. Chem. 2002, 277:7341-7347.

118. Mueller, S. et al: Interaction of the poliovirus receptor CD155 with the dynein light chain tctex-1 and its implication for poliovirus pathogenesis. J. Biol. Chem. 2002, 277:7897-7904.

119. Cunningham, S.A. et al: JAM2 interacts with alpha-4-beta-1. facilatation by JAM3. J. Biol. Chem. 2002, 277:27589-27592.

120. Santra, M. et al: Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope. J. Biol. Chem. 2002, 277:35671-35681.

121. Zheng, Y. et al: Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1. J. Biol. Chem. 2002, 277:42463-42470.

122. McCudden, C.R. et al: Characterization of mammalian stanniocalcin receptors. Mitochondrial targeting of ligand and receptor for regulation of cellular metabolism. J. Biol. Chem. 2002, 277:45249-45258.

123. Koolpe, M. et al: An ephrin mimetic peptide that selectively targets the EphA2 receptor. J. Biol. Chem. 2002, 277:46974-46979.

124. Fujii, T. et al: Caenorhabditis elegans PlexinA, PLX-1, interacts with transmembrane semaphorins and regulates epidermal morphogenesis. Development. 2002, 129: 2053-2063.

125. Nishida, K. et al: Domain-specific olivocerebellar projection regulated by the EphA-ephrin-A interaction. Development. 2002, 129:5647-5658.

126. Mu, D. et al: The integrin vß8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-ß1. J. Cell Biology. 2002, 157:493-507.

127. Pasterkamp, R.J. et al: Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature. 2003, 424:398-405.

128. Lee, H.-H. et al: Jelly belly protein activates teh receptor tyrosine kinase Alk to specify visceral muscle pioneers. Nature. 2003, 425:507-512.

129. Bogatcheva, N.V. et al: GREAT/LGR8 is the only receptor for insulin-like 3 peptide. Mol. Endocrinology. 2003, 17:2639-2646.

130. Truong, A. et al: Isolation and expression analysis of the canine insulin-like factor 3 gene. Biol. Reproduction. 2003, 69:1658-1664.

131. Artigiani, S. et al: Functional regulation of semaphorin receptors by proprotein convertases. J. Biol. Chem. 2003, 278:10094-10101.

132. Chesneau, V. et al: Catalytic properties of ADAM19. J. Biol. Chem. 2003, 278:22331-22340.

133. Mueller, S. and Wimmer, E.: Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha-v-beta-3 integrin-containing membrane microdomains. J. Biol. Chem. 2003, 278:31251-31260.

134. Kikuchi, K. et al: in vitro and in vivo characterization of a novel Semaphorin 3A inhibitor, SM-216289 or Xanthofulvin. J. Biol. Chem. 2003, 278:42985-42991.

135. Porter, D. et al: A neural survival factor is a candidate oncogene in breast cancer. Proc. Natl. Acad. Sci. USA. 2003, 100:10931-10936.

136. Oertle, T. et al: Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. Journal of Neuroscience. 2003, 23:5393-5406.

137. Ding, Z.B. et al: Sex-peptides bind to two molecularly different targets in Drosophila melanogaster females. J. Neurobiology. 2003, 55:372-384.

138. Sajnani-Perez, G. et al: Isoform-specific binding of the tyrosine phosphatase PTP sigma to a ligand in developing muscle. Molecular and Cellular Neuroscience. 2003, 22:37-48.

139. He, Y. et al: Complexes of poliovirus serotypes with their common cellular receptor, CD155. J. Virology. 2003, 77:4827-4835.

140. Brennan, C. and Fabes, J.: Alkaline phosphatase fusion proteins as affinity probes for protein localization studies. Science's STKE. 2003, 2003:pl2.

141. Hymowitz, S.G. et al: The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity. Structure. 2003, 11:1513-1520.

142. Xu, Q. et al: Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell. 2004, 116:883-895.

143. Umemori, H. et al: FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain. Cell. 2004, 118:257-270.

144. Allinen, M. et al: Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell. 2004, 6:17-32.

145. Nanda, A. et al: TEM8 interacts with the cleaved C5 domain of collagen alpha-3(VI). Cancer Research. 2004, 64:817-820.

146. Nanda, A. et al: Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Research. 2004, 64:8507-8511.

147. Watanabe, Y. et al: Navigation of trochlear motor axons along the midbrain-hindbrain boundary by neuropilin 2. Development. 2004, 131:681-692.

148 Tian, H. et al: Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development. 2004, 131:4021-4033.

149. Wakamatsu, Y. et al: Expression of a novel secreted factor, Seraf indicates an early segregation of Schwann cell precursors from neural crest during avian development. Developmental Biology. 2004, 268:162-173.

150. Zhou, H.-M. et al: Essential role for ADAM19 in cardiovascular morphogenesis. Mol. Cell. Biol. 2004, 24:96-104.

151. Choisy-Rossi, C.-M. et al: Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience. J. Immunology. 2004, 173:3791-3800.

152. Persaud, K. et al: Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C. J. Cell Science. 2004, 117:2745-2756.

153. Wang, S. et al: QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis. Proc. Natl. Acad. Sci. USA. 2004, 101:4833-4838.

154. Sahin, U. et al: Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J. Cell Biology. 2004, 164:769-779.

155. Samad, T.A. et al: DRAGON: A member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. Journal of Neuroscience. 2004, 24:2027-2036.

156. Brinks, H. et al: The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus. Journal of Neuroscience. 2004, 24:3862-3869.

157. Kawamoto, Y. et al: Identification of RET autophosphorylation sites by mass spectrometry. J. Biol. Chem. 2004, 279:14213-14224.

158. Zheng, Y. et al: Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFa) shedding and of the function of the TNFa ectodomain in ensuring selective stimulated shedding by the TNFa convertase (TACE/ADAM17). J. Biol. Chem. 2004, 279:42898-42906.

159. Gline, S.E. et al: A 50A separation of the integrin alpha-v-beta-3 extracellular domain C-termini reveals an intermediate activation state. J. Biol. Chem. 2004, 10.1074/jbc.M406582200 (in press).

160. Karatan, E. et al: Molecular recognition properties of FN3 monobodies that bind the Src SH3 domain. Chemistry and Biology. 2004, 11:835-844.

161. Okajima, T. et al: Chaperone activity of protein O-fucosyltransferase 1 promotes Notch receptor folding. Science. 2005, 307:1599-1603.

162. Chen, I. et al: Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase. Nature Methods. 2005, 2:99-104.

163. Yamamoto, A. et al: Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. Cell. 2005 120:223-235.

164. Park, J.B. et al: A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors. Neuron. 2005, 45:345-351.

165. Shao, Z. et al: TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron. 2005, 45:353-359.

166. Li, X. et al: Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling J. Biol. Chem. 2005, 280:19883-19887.

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