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Endo180 antibodies
Endo180 (uPARAP, CD280) is a collagen binding factor and member of the mannose receptor family which also includes the mannose receptor (MR), the M-type phospho-lipase A2(PLA2R) receptor, and DEC-205. All 4 receptors contain an N-terminal cysteine-rich domain, a fibronectin type II (FNII) domain, 8 C-type-lectin domains (CTLDs; 10 in the case of DEC-205), a single transmembrane domain, and a short cytoplasmic domain. Endo180 has been shown to be a collagen receptor and functions in both collagen turnover and cell adhesion.
GenHunter has 4 monoclonal antibodies against human Endo180 (a neutralizing mAb and 3 binding mAbs) plus a recombinant human Endo180-Fc fusion protein.
