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- Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal [MA301N-100 or MA301N-025]
Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal [MA301N-100 or MA301N-025]
Product Description
Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal [MA301N-100 or MA301N-025]
Endo180 (uPARAP, CD280) is a collagen binding factor and member of the mannose receptor family which also includes the mannose receptor (MR), the M-type phospho-lipase A2(PLA2R) receptor, and DEC-205. All 4 receptors contain an N-terminal cysteine-rich domain, a fibronectin type II (FNII) domain, 8 C-type-lectin domains (CTLDs; 10 in the case of DEC-205), a single transmembrane domain, and a short cytoplasmic domain. Endo180 has been shown to be a collagen receptor and functions in both collagen turnover (Reference 1, see below) and cell adhesion (2).
GenHunter has 4 monoclonal antibodies against human Endo180 (a neutralizing mAb and 3 binding mAbs), an antibody against Trimer-Tag (human CICP, Type 1 Collagen), plus a recombinant human Endo180-Fc fusion protein.
Endo180 Antibody & Antigen Products Available:
Product Description | Clone | Isotype | Specificity | Volume | Applications |
Cat. No. |
Click to Order |
Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal | 9F12-E3 | Not tested |
Human Endo180 (D2-D3) |
100µg or 25µg |
NAb, ELISA,WB |
Order | |
Human Endo180 (D1) Binding Antibody, Mouse Monoclonal | 10H4-D4 | Not tested |
Human Endo180 (D1) |
100µg or 25µg |
ELISA,WB |
Order | |
Human Endo180 (D4) Binding Antibody, Mouse Monoclonal | 7H12-E10 | Not tested |
Human Endo180 (D4) |
100µg or 25µg |
ELISA,WB |
Order | |
Human Endo180 (D6) Binding Antibody, Mouse Monoclonal | 15C12-C11 | Not tested |
Human Endo180 (D6) |
100µg or 25µg |
ELISA,WB |
Order | |
Trimer-Tag (Human CICP, Type I Collagen) Binding Antibody, Mouse Monoclonal | 14-D3 | Not tested |
Trimer-Tag (Human CICP, |
100µg or 25µg |
ELISA,WB |
Order | |
Recombinant Human Endo180-Fc Fusion Protein |
|
100µg or 25µg |
|
Order |
We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus), HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).
References:
- Wienke, D. et al: Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor. (2003) Molecular Biology of the Cell. 14:3592-3604. https://www.molbiolcell.org/doi/10.1091/mbc.e02-12-0814
- Thomas, E.K. et al: Endo180 Binds to the C-terminal Region of Type I Collagen. (2005) Journal of Biological Chemistry. 280:22596-22605. https://www.jbc.org/article/S0021-9258(20)61425-9/fulltext
All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Antibody Specifications | |
Antibody Name |
Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal |
Clone No. | 9F12-E3 |
Class | Mouse Monoclonal |
Catalog No / SKU | MA301N-100 (for 100 µg) or MA301N-025 (for 25 µg) |
IgG subtype | Not tested |
Specificity | Human Endo180 (D2-D3) |
Binding / Neutralizing mAb | Neutralizing mAb (NAb) |
Volume | 25 or 100 ug |
Provided as | Liquid |
Applications | Neutralizing antibody: EC50 = 164 ng/mL D1-D3, 134 ng/mL D1-D4, 473 ng/mL Endo180 ELISA: antigen binding affinity EC50 = 5.5 ng/mL D1-D3, 34 ng/mL D1-D4, 40 ng/mL Endo180 Western Blot at 1:1000 - 1:2000 |
Concentration | ~ 1 mg/mL |
Purification | G protein affinity purified, >99% determined by HPLC |
Storage conditions | Store at -20°C long term, Avoid freeze / thaw cycle |
All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Documents
Endo180 Antibody & Antigen Products Available:
Product Description | Clone | Isotype | Specificity | Volume | Applications |
Cat. No. |
Click to Order |
Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal | 9F12-E3 | Not tested |
Human Endo180 (D2-D3) |
100µg or 25µg |
NAb, ELISA,WB |
Order | |
Human Endo180 (D1) Binding Antibody, Mouse Monoclonal | 10H4-D4 | Not tested |
Human Endo180 (D1) |
100µg or 25µg |
ELISA,WB |
Order | |
Human Endo180 (D4) Binding Antibody, Mouse Monoclonal | 7H12-E10 | Not tested |
Human Endo180 (D4) |
100µg or 25µg |
ELISA,WB |
Order | |
Human Endo180 (D6) Binding Antibody, Mouse Monoclonal | 15C12-C11 | Not tested |
Human Endo180 (D6) |
100µg or 25µg |
ELISA,WB |
Order | |
Trimer-Tag (Human CICP, Type I Collagen) Binding Antibody, Mouse Monoclonal | 14-D3 | Not tested |
Trimer-Tag (Human CICP, |
100µg or 25µg |
ELISA,WB |
Order | |
Recombinant Human Endo180-Fc Fusion Protein |
|
100µg or 25µg |
|
Order |
We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus), HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).
All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.