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Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal [MA301N-100 or MA301N-025]

$350.00
SKU:
MA301N-100
Quantity:
Description
Specifications
Ordering
Documents

Product Description

Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal [MA301N-100 or MA301N-025] 

Endo180 (uPARAP, CD280) 
is a collagen binding factor and member of the mannose receptor family which also includes the mannose receptor (MR), the M-type phospho-lipase A2(PLA2R) receptor, and DEC-205. All 4 receptors contain an N-terminal cysteine-rich domain, a fibronectin type II (FNII) domain, 8 C-type-lectin domains (CTLDs; 10 in the case of DEC-205), a single transmembrane domain, and a short cytoplasmic domain. Endo180 has been shown to be a collagen receptor and functions in both collagen turnover (Reference 1, see below) and cell adhesion (2).

GenHunter has 4 monoclonal antibodies against human Endo180 (a neutralizing mAb and 3 binding mAbs), an antibody against Trimer-Tag (human CICP, Type 1 Collagen), plus a recombinant human Endo180-Fc fusion protein.


Endo180 Antibody & Antigen Products Available:

Product Description   Clone   Isotype  Specificity          Volume   Applications

  Cat. No.                         

Click to Order

Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal 9F12-E3    Not tested

Human Endo180 (D2-D3)

100µg
or 25µg

NAb, ELISA,WB

MA301N-100

MA301N-025

Order
Human Endo180 (D1) Binding Antibody, Mouse Monoclonal 10H4-D4    Not tested

Human Endo180 (D1)

100µg
or 25µg 

ELISA,WB

MA302B-100

MA302B-025

Order
Human Endo180 (D4) Binding Antibody, Mouse Monoclonal 7H12-E10    Not tested

Human Endo180 (D4)

100µg
or 25µg 

ELISA,WB

MA303B-100

MA303B-025

Order
Human Endo180 (D6) Binding Antibody, Mouse Monoclonal 15C12-C11    Not tested

Human Endo180 (D6)

100µg
or 25µg 

ELISA,WB

MA304B-100

MA304B-025

Order
Trimer-Tag (Human CICP, Type I Collagen) Binding Antibody, Mouse Monoclonal 14-D3    Not tested

Trimer-Tag (Human CICP,
Type I Collagen)

100µg
or 25µg 

ELISA,WB

MA501B-100

MA501B-025

Order
Recombinant Human Endo180-Fc Fusion Protein      

 

100µg
or 25µg 

 

MP205-100

MP205-025

Order

We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus)HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).


References:

  1. Wienke, D. et al: Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor. (2003) Molecular Biology of the Cell. 14:3592-3604. https://www.molbiolcell.org/doi/10.1091/mbc.e02-12-0814
  2. Thomas, E.K. et al: Endo180 Binds to the C-terminal Region of Type I Collagen. (2005) Journal of Biological Chemistry. 280:22596-22605. https://www.jbc.org/article/S0021-9258(20)61425-9/fulltext

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Antibody Specifications
Antibody Name

Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal

Clone No. 9F12-E3 
Class Mouse Monoclonal
Catalog No / SKU MA301N-100 (for 100 µg) or MA301N-025 (for 25 µg)
IgG subtype Not tested
Specificity Human Endo180 (D2-D3)
Binding / Neutralizing mAb       Neutralizing mAb (NAb)
Volume 25 or 100 ug
Provided as Liquid
Applications Neutralizing antibody: EC50 = 164 ng/mL D1-D3, 134 ng/mL D1-D4, 473 ng/mL Endo180
ELISA: antigen binding affinity EC50 = 5.5 ng/mL D1-D3, 34 ng/mL D1-D4, 40 ng/mL Endo180
Western Blot at 1:1000 - 1:2000
Concentration ~ 1 mg/mL
Purification G protein affinity purified, >99% determined by HPLC
Storage conditions Store at -20°C long term, Avoid freeze / thaw cycle

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Documents

 

Endo180 Antibody & Antigen Products Available:

Product Description   Clone   Isotype  Specificity          Volume   Applications

  Cat. No.                         

Click to Order

Human Endo180 (D2-D3) Neutralizing Antibody, Mouse Monoclonal 9F12-E3    Not tested

Human Endo180 (D2-D3)

100µg
or 25µg

NAb, ELISA,WB

MA301N-100

MA301N-025

Order
Human Endo180 (D1) Binding Antibody, Mouse Monoclonal 10H4-D4    Not tested

Human Endo180 (D1)

100µg
or 25µg 

ELISA,WB

MA302B-100

MA302B-025

Order
Human Endo180 (D4) Binding Antibody, Mouse Monoclonal 7H12-E10    Not tested

Human Endo180 (D4)

100µg
or 25µg 

ELISA,WB

MA303B-100

MA303B-025

Order
Human Endo180 (D6) Binding Antibody, Mouse Monoclonal 15C12-C11    Not tested

Human Endo180 (D6)

100µg
or 25µg 

ELISA,WB

MA304B-100

MA304B-025

Order
Trimer-Tag (Human CICP, Type I Collagen) Binding Antibody, Mouse Monoclonal 14-D3    Not tested

Trimer-Tag (Human CICP,
Type I Collagen)

100µg
or 25µg 

ELISA,WB

MA501B-100

MA501B-025

Order
Recombinant Human Endo180-Fc Fusion Protein      

 

100µg
or 25µg 

 

MP205-100

MP205-025

Order

We also have many other antibody and antigen products (CLICK HERE or names below) including for:
SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), Human VEGF-R, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, Trimer-Tag, RSV (Respiratory Syncytial Virus)HSV-2 (Herpes Simplex Virus 2), and AP (alkaline phosphatase).



All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.