COL1A1 (Human Collagen type I, alpha-1 chain) Antibody, Mouse Monoclonal [MA321B-100 or MA321B-025] 

GenHunter currently has monoclonal antibodies against Collagen Type I & III, 4 monoclonal antibodies against Endo180, & 1 against Trimer-Tag (Human CICP, Type I Collagen). See below for more info.

Collagen is the most abundant structural protein in mammals, constituting roughly 25-30% of total body protein. It acts as the major component of extracellular matrix and the primary "glue" or scaffolding providing strength, elasticity, and structural support to skin, bones, tendons, ligaments, and connective tissues.

Structure
• Triple Helix: Collagen is characterized by a unique triple-helix structure, where three polypeptide alpha-chains are tightly wound together, creating a rigid and strong configuration.
• Amino Acid Composition: It is rich in glycine, proline, and hydroxyproline, with glycine appearing every third amino acid, allowing for a tight, stable packing.
• Hierarchical Assembly: These triple-helix molecules, known as tropocollagen, assemble into fibrils that form fibers and networks.
• Types: There are at least 28 different types, with Type I being the most common, accounting for 90% of the collagen in the human body. Functions
• Structural Integrity: Provides tensile strength and structure to skin, bone, tendons, cartilage, and ligaments, ensuring they can withstand stretching.
• Tissue Repair and Growth: Essential in the extracellular matrix to support cell migration, tissue regeneration, and wound healing.
• Elasticity and Health: Maintains skin elasticity and supports joint health.
• Organ Protection: Acts as a protective covering for organs and aids in blood vessel structure.

Collagen production naturally declines with age, leading to decreased tissue strength.

Type III collagen is a vital fibrous protein and the second most abundant type of collagen in the human body. It is a key structural component of the extracellular matrix (ECM) found in soft, extensible tissues, particularly in the skin, lungs, intestines, and the walls of blood vessels. It works alongside Type I collagen to provide structural integrity, elasticity, and support for tissues that need to expand and recoil.

Collagen Antibody Products Available:

Monoclonal Antibody Description	Clone	Isotype	Specificity	Volume	Applications	Cat. No.	Click to Order
COL1A1 (Human Collagen type I, alpha-1 chain) Antibody, Mouse Monoclonal	16F4-D6	Not tested	COL1A1	100µg or 25µg	ELISA,WB	MA321B-100 MA321B-025	Order
COL3A1 (Human Collagen type III, alpha-1 chain) Antibody, Mouse Monoclonal	7B4-H9	Not tested	COL3A1	100µg or 25µg	ELISA,WB	MA323B-100 MA323B-025	Order

We also have many other primary antibodies, secondary antibodies, & antigen products (CLICK HERE or the names below) for:  SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), TPO (Thrombopoietin), Human VEGF-R, Collagen, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, TRIMER-TAG, RSV (Respiratory Syncytial Virus), HSV-2 (Herpes Simplex Virus 2), VZV (Varicella Zoster Virus), Influenza (Flu-A & Flu-B), PIV (Parainfluenza virus), hMPV (human metapneumovirus), AP (alkaline phosphatase), PEDV (porcine epidemic diarrhea virus), PRRSV (porcine reproductive respiratory sydrome virus), plus Secondary Antibodies (for human, porcine, feline, & canine), & Vaccine Adjuvents.

References:

1. References coming soon

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.