Human parainfluenza virus 2 (PIV2) Antibody, Mouse Monoclonal [MA750B-100 or MA750B-025] 

Human Parainfluenza Viruses (hPIV/PIV) are a group of common respiratory viruses (e.g. PIV1, PIV2, PIV3, and PIV4) belonging to the Paramyxoviridae family, known for causing upper and lower respiratory tract illnesses, primarily in infants and children.

Key Aspects of PIV:
• Symptoms: Generally cause mild cold-like symptoms, including fever, runny nose, and cough.
• Transmission: Spread through respiratory droplets (coughing/sneezing) and contaminated surfaces.
• Seasonality: PIV-1 and PIV-2 tend to peak in the fall, while PIV-3 is endemic year-round with peaks in spring and summer.
• Management: No licensed vaccine or antiviral treatment exists; management is focused on relieving symptoms.

Human Parainfluenza Virus Type 3 (PIV3)
PIV3 is considered the most virulent and commonly detected serotype among the four types, causing significant morbidity and mortality, especially in children and immunocompromised patients.
• Clinical Significance: PIV3 is the second most common cause of lower respiratory tract infection (LRTI) in children behind Respiratory Syncytial Virus (RSV) - we also have 9 RSV-related antibodies.
• Primary Infections: It often infects infants within the first year of life, frequently leading to bronchiolitis, bronchitis, and pneumonia.
• Severe Cases: It can cause severe disease and high mortality rates in hematopoietic cell transplant (HCT) recipients and immunocompromised adults.
• Distinguishing Features: Unlike PIV-1 and -2, which are strongly associated with croup, PIV-3 is more often associated with deeper lung involvement and outbreaks in nurseries.
• Transmission Duration: Infected children can shed the virus up to 1-3 weeks after symptoms end.

PIV3 is highly infectious, and while most infections in healthy individuals are self-limiting, the high morbidity in vulnerable populations has made it a key target for vaccine development.

GenHunter currently has 4 monoclonal antibodies against PIV.

PIV Antibody Products Available:

Monoclonal Antibody Description	Clone	Isotype	Specificity	Volume	Applications	Cat. No.	Click to Order
Human parainfluenza virus 2 (PIV2) Antibody, Mouse Monoclonal	4D7-H11	Not tested	PIV2	100µg or 25µg	ELISA,WB	MA750B-100 MA750B-025	Order
Human parainfluenza virus 3 (PIV3) Antibody, Mouse Monoclonal	82C8-C8	Not tested	PIV3	100µg or 25µg	ELISA,WB	MA751B-100 MA751B-025	Order
Human parainfluenza virus 3 (PIV3)-Pre Specific Antibody, Mouse Monoclonal	92C9-F10	Not tested	PIV3-Pre	100µg or 25µg	ELISA,WB	MA755B-100 MA755B-025	Order
Human parainfluenza virus 4 (PIV4) Antibody, Mouse Monoclonal	3G9-H11	Not tested	PIV4	100µg or 25µg	ELISA,WB	MA757B-100 MA757B-025	Order

We also have many other primary antibodies, secondary antibodies, & antigen products (CLICK HERE or the names below) for:  SARS-CoV-2 (COVID-19), Human IL-24, Human IL-20R2, Nplate (Romiplostim), TPO (Thrombopoietin), Human VEGF-R, Collagen, Endo180 (uPARAP, CD280), Tumor Necrosis Factor (TNF) superfamily, SIRPα (Signal-regulatory protein alpha), Rabies virus, TRIMER-TAG, RSV (Respiratory Syncytial Virus), HSV-2 (Herpes Simplex Virus 2), VZV (Varicella Zoster Virus), Influenza (Flu-A & Flu-B), PIV (Parainfluenza virus), hMPV (human metapneumovirus), AP (alkaline phosphatase), PEDV (porcine epidemic diarrhea virus), PRRSV (porcine reproductive respiratory sydrome virus), plus Secondary Antibodies (for human, porcine, feline, & canine), & Vaccine Adjuvents.

References:

1. References coming soon

All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.